Ecological therapeutic opportunities for oral diseases
Identifieur interne : 000276 ( Main/Exploration ); précédent : 000275; suivant : 000277Ecological therapeutic opportunities for oral diseases
Auteurs : Anilei Hoare [États-Unis] ; Philip D. Marsh [Royaume-Uni] ; Patricia I. Diaz [États-Unis]Source :
- Microbiology spectrum [ 2165-0497 ] ; 2017.
Abstract
The three main oral diseases of humans, that is caries, periodontal diseases and oral candidiasis, are associated with microbiome shifts initiated by changes in the oral environment and/or decreased effectiveness of mucosal immune surveillance. In this review we discuss the role that microbial-based therapies may have in the control of these conditions. Most investigations on the use of microorganisms for management of oral disease have been conducted with probiotic strains with some positive but very discrete clinical outcomes. Other strategies such as whole oral microbiome transplantation or modification of community function by enrichment with health-promoting indigenous oral strains may offer more promise but research in this field is still in its infancy. Any microbial-based therapeutics for oral conditions, however, are likely to be only one component within a holistic preventive strategy that should also aim at modification of the environmental influences responsible for the initiation and perpetuation of microbiome shifts associated with oral dysbiosis.
Url:
DOI: 10.1128/microbiolspec.BAD-0006-2016
PubMed: 28840820
PubMed Central: 5573124
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002669
- to stream Pmc, to step Curation: 002669
- to stream Pmc, to step Checkpoint: 000255
- to stream Ncbi, to step Merge: 007155
- to stream Ncbi, to step Curation: 007155
- to stream Ncbi, to step Checkpoint: 007155
- to stream Main, to step Merge: 000276
- to stream Main, to step Curation: 000276
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ecological therapeutic opportunities for oral diseases</title>
<author><name sortKey="Hoare, Anilei" sort="Hoare, Anilei" uniqKey="Hoare A" first="Anilei" last="Hoare">Anilei Hoare</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marsh, Philip D" sort="Marsh, Philip D" uniqKey="Marsh P" first="Philip D." last="Marsh">Philip D. Marsh</name>
<affiliation wicri:level="4"><nlm:aff id="A2">Division of Oral Biology, School of Dentistry, University of Leeds, Leeds, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Oral Biology, School of Dentistry, University of Leeds, Leeds</wicri:regionArea>
<orgName type="university">Université de Leeds</orgName>
<placeName><settlement type="city">Leeds</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Yorkshire-et-Humber</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Diaz, Patricia I" sort="Diaz, Patricia I" uniqKey="Diaz P" first="Patricia I." last="Diaz">Patricia I. Diaz</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28840820</idno>
<idno type="pmc">5573124</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573124</idno>
<idno type="RBID">PMC:5573124</idno>
<idno type="doi">10.1128/microbiolspec.BAD-0006-2016</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">002669</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002669</idno>
<idno type="wicri:Area/Pmc/Curation">002669</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002669</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000255</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000255</idno>
<idno type="wicri:Area/Ncbi/Merge">007155</idno>
<idno type="wicri:Area/Ncbi/Curation">007155</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">007155</idno>
<idno type="wicri:Area/Main/Merge">000276</idno>
<idno type="wicri:Area/Main/Curation">000276</idno>
<idno type="wicri:Area/Main/Exploration">000276</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Ecological therapeutic opportunities for oral diseases</title>
<author><name sortKey="Hoare, Anilei" sort="Hoare, Anilei" uniqKey="Hoare A" first="Anilei" last="Hoare">Anilei Hoare</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marsh, Philip D" sort="Marsh, Philip D" uniqKey="Marsh P" first="Philip D." last="Marsh">Philip D. Marsh</name>
<affiliation wicri:level="4"><nlm:aff id="A2">Division of Oral Biology, School of Dentistry, University of Leeds, Leeds, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Oral Biology, School of Dentistry, University of Leeds, Leeds</wicri:regionArea>
<orgName type="university">Université de Leeds</orgName>
<placeName><settlement type="city">Leeds</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Yorkshire-et-Humber</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Diaz, Patricia I" sort="Diaz, Patricia I" uniqKey="Diaz P" first="Patricia I." last="Diaz">Patricia I. Diaz</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Periodontology, Department of Oral Health and Diagnostic Sciences, UConn Health, Farmington, CT</wicri:regionArea>
<placeName><region type="state">Connecticut</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Microbiology spectrum</title>
<idno type="eISSN">2165-0497</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>SUMMARY</title>
<p id="P1">The three main oral diseases of humans, that is caries, periodontal diseases and oral candidiasis, are associated with microbiome shifts initiated by changes in the oral environment and/or decreased effectiveness of mucosal immune surveillance. In this review we discuss the role that microbial-based therapies may have in the control of these conditions. Most investigations on the use of microorganisms for management of oral disease have been conducted with probiotic strains with some positive but very discrete clinical outcomes. Other strategies such as whole oral microbiome transplantation or modification of community function by enrichment with health-promoting indigenous oral strains may offer more promise but research in this field is still in its infancy. Any microbial-based therapeutics for oral conditions, however, are likely to be only one component within a holistic preventive strategy that should also aim at modification of the environmental influences responsible for the initiation and perpetuation of microbiome shifts associated with oral dysbiosis.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Connecticut</li>
<li>Yorkshire-et-Humber</li>
</region>
<settlement><li>Leeds</li>
</settlement>
<orgName><li>Université de Leeds</li>
</orgName>
</list>
<tree><country name="États-Unis"><region name="Connecticut"><name sortKey="Hoare, Anilei" sort="Hoare, Anilei" uniqKey="Hoare A" first="Anilei" last="Hoare">Anilei Hoare</name>
</region>
<name sortKey="Diaz, Patricia I" sort="Diaz, Patricia I" uniqKey="Diaz P" first="Patricia I." last="Diaz">Patricia I. Diaz</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Marsh, Philip D" sort="Marsh, Philip D" uniqKey="Marsh P" first="Philip D." last="Marsh">Philip D. Marsh</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000276 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000276 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Main |étape= Exploration |type= RBID |clé= PMC:5573124 |texte= Ecological therapeutic opportunities for oral diseases }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28840820" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
This area was generated with Dilib version V0.6.32. |